Sandrine Fraboulet

Date du document : 31 mars 2014
Dernière mise à jour le : 31 mars 2014

Sandrine.Fraboulet@ujf-grenoble.fr

Education / Graduation / Career

  • 1993 - Ecole Normale Supérieure de Lyon, Université Claude Bernard Lyon I - Master of Biology
  • 1997 - Université Aix-Marseille 2 - PhD in Cellular communications in endocrinology
  • 1997-2000 - Institut de bIologie du dévelopement Marseille, Institu Albert Bonniot Grenoble - Post-Doctoral Position

Teaching: The main disciplines

  • Cellular Biology
  • Neurobiology, Histology
  • Molecular Biology

Research Topics

  • Alix and ESCRT proteins functions in neurons
  • Exosomes as a novel way of intercellular communication

Publications

  • Chivet M, Hemming F, Pernet-Gallay K, Fraboulet S, Sadoul R. 2012. Emerging role of neuronal exosomes in the central nervous system. Front Physiol. 3:145. 
  • A.L. Mahul-Mellier, F. Strappazzon, C. Chatellard-Causse, B. Blot, D. Béal, S. Torch,F. Hemming, A. Petiot, J.M. Verna, S. Fraboulet*, R.Sadoul*. 2009. Alix and ALG-2 make a link between endosomes and neuronal death. Biochem Soc Trans. 37(Pt 1):200-3.
  • Briese M, Esmaeili B, Fraboulet S, Burt EC, Christodoulou S, Towers PR, Davies KE, Sattelle DB. 2009. Deletion of smn-1, the Caenorhabditis elegans orthologue of the spinal muscular atrophy gene, results in locomotor dysfunction and reduced lifespan. Hum Mol Genet. 18(1):97-104
  • A.L. Mahul-Mellier, F. Strappazzon, A. Petiot, C. Chatellard-Causse, S. Torch, B. Blot, K. Freeman, L. Kuhn, J. Garin, J.M. Verna, S. Fraboulet*, R.Sadoul*. 2008. Alix and ALG-2 are involved in TNF-R1 induced cell death. J Biol Chem 283(50):34954-65.* co-auteurs
  • A.L. Mahul-Mellier, F.J. Hemming, B. Blot, S. Fraboulet* and R. Sadoul*. 2006. Alix, making a link between apoptosis-linked gene-2, the endosomal sorting complexes required for transport, and neuronal death in vivo. Journal of Neuroscience, 26 (2): 542-549.* co-auteurs.
  • J. A. Weiner, S. J. Koo, S. Nicolas, S. Fraboulet, S. L. Pfaff, O. Pourquié, and J. R. Sanes. 2004. Axon fasciculation defects and retinal dysplasias in mice lacking the immunoglobulin superfamily adhesion molecule BEN/ALCAM/SC. Molecular and Cellular Neuroscience, 27: 59-69.
  • F. J. Hemming, S. Fraboulet, B. Blot, R. Sadoul. 2004. Early increase of Alix in areas of kainate-induced neurodegeneration. Neuroscience, 123: 887-895.
  • T. A. Mitsiadis, S. Fraboulet, O. Pourquié, P. T. Sharpe, K. Kavvadia. 2003. BEN/DM-GRASP/SC1 expression during mouse facial development: differential expression and regulation in molars and incisors. Gene expression patterns, 3 (3): 255-9.
  • S. Fraboulet, F. J. Hemming, A.L. Mahul, N. Cristina, R. Sadoul. 2003. Expression of Alix protein during early avian development. Gene expression patterns, 3 (2): 139-42.
  • I. Olivera-Martinez, S. Missier, S. Fraboulet, J. Thelu, D. Dhouailly. 2002. Differential regulation of the chick dorsal thoracic progenitors from the medial dermomyotome. Development 129 (20): 4763-72.