Dr. Virginie Stoppin-Mellet
Date du document : 21 janvier 2014
Dernière mise à jour le : 18 février 2014
Education / Graduation / Career
- 1991 - Strasbourg I - Molecular and Cell Biology
- 1991-1994 - Strasbourg I - PhD in Plant Molecular & Cell Biology
- 1994-1995 - Johns Hopkins University - Post-Doctoral Position
Teaching: The main disciplines
- Cell Biology
- Microtubule and actin cytoskeleton
- Portran D, Zoccoler M, Gaillard J, Stoppin-Mellet V, Neumann E, Arnal I, Martiel JL, Vantard M. (2013) MAP65/Ase1 promote microtubule flexibility. Mol Biol Cell. 24(12) : 1964-73
- Stoppin-Mellet V, Fache V, Portran D, Martiel J-L, Vantard M (2013) MAP65 coordinate microtubule growth during bundle formation. PLoS ONE 8(2): e56808.
- Fache V, Gaillard J, Van Damme D, Geelen D, Neumann E, Stoppin-Mellet V, Vantard M. (2010) Arabidopsis kinetochore fiber-associated MAP65-4 cross-links microtubules and promotes microtubule bundle elongation. Plant Cell 22(11): 3804-15.
- Gaillard J, Neumann E, Van Damme D, Stoppin-Mellet V, Ebel C, Barbier E, Geelen D, Vantard M. (2008) Two microtubule-associated proteins of Arabidopsis MAP65s promote antiparallel microtubule bundling. Mol Biol Cell. 19(10): 4534-44.
- Stoppin-Mellet V, Gaillard J, Vantard M. (2006) Katanin's severing activity favors bundling of cortical microtubules in plants. Plant J. 46(6):1009-17.
- Wicker-Planquart, C., Stoppin-Mellet, V., Blanchoin, L. and Vantard, M. (2004). Interactions of tobacco microtubule-associated protein MAP65-1b with microtubules Plant J. 39(1): 126 - 134
- Stoppin-Mellet, V., Gaillard, J. and Vantard, M. (2002). Functional evidence for in vitro microtubule severing by the plant katanin homologue Biochem. J. 365: 337-342
- Erhardt, M., Stoppin-Mellet, V., Campagne, S., Canaday, J., Mutterer, J., Fabian, T., Sauter, M., Muller, T., Peter, C., Lambert, A. M. and Schmit, A. C. (2002). The plant Spc98p homologue colocalizes with gamma-tubulin at microtubule nucleation sites and is required for microtubule nucleation. J. Cell Sci. 115(11): 2423-2431
- Stoppin V., Lambert A.M., Vantard M. (1996) Plant microtubule-associated proteins (MAPs) affect microtubule nucleation and growth at plant nuclei and mammalian centrosomes. Eur. J. Cell Biol. 69, 11-23.
- Stoppin V., Vantard M., Schmit A.C., Lambert A.M. (1994) Isolated plant nuclei nucleate microtubule assembly : the nuclear surface in higher plants has centrosome-like activity. Plant Cell 6, 1099-1106.
Interests, Projects, Ideas
My job is part time teaching and part time research. In my opinion, teaching is an exciting and a very challenging activity. You need to efficiently provide students with multiple and various knowledge, and most importantly you need to give them clues to acquire autonomy and sense of criticism so that they can handle problems by their own. This latter point is the great challenge of modern education, because nowadays information is accessible to anyone. Grenoble University of Sciences is an innovative place where teachers develop tools to help students toward success. I feel proud to be part of this adventure. As a researcher, I became fascinated by the beauty of cells. I am amazed by their so efficient organization, each organelle or molecule being at the right place at the right time, so that cells ensure their multiple functions and communicate with their environment. I am working on the internal cell skeleton, called the cytoskeleton, which is a dynamic network of cables and tubes that generate form and motion in living cells. I focus my interest on the microtubule network of neural cells, whose abnormalities are found in numerous neuropathies as Alzheimer disease. This research is done at the Grenoble Institute of Neurosciences, in Arnal’s lab. The place to be!